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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a09375fdd303a7c8c6855a7f2c86fc3b503692e7b9d56d848bacc364e3856aa' 
  AND token = 'R37+YeAvvuEx4js0OoevWX/WFX7eW1sK88JEVhNXVwg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}