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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '413541ccf8d076356ab8138d61e8d4603e9f5406e5fdce6bf181a862e0c66c25' 
  AND token = 'S/E4iWYvr7mieSIpFTReu2ZUIYteOKh2iymUKVN8xGU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}