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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21102c678f5ce6e83806da7a50a3f73c25f32556122281ea3166ea6f68d04610' 
  AND token = '0HP6bL2Bpsd5V6gkQHmvXr6f13XHj4t/q2K2/gSn++A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}