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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd567032fb66dda0dcca03e519f937843b345da40e5fffc8b41eac2d1e916c2db' 
  AND token = '289zDR8E7po37D8OePu/HSDhNsdHrodUsJsBrR14bRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}