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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '59f52dcefe94da00a3df27f6073be795134f861ff3e13102fa9624297b550d1a' 
  AND token = 'DZK0Q36uWMf7zEn46sJPQuKCXn0WRCM3AAzQkvzMp4A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}