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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '10a1ad12f6cbac00ba39b8df23258cd16fff4f65c713e0481d8b426650deb5f0' 
  AND token = 'lx/lJyr6dtj1KsEtA7ulDZOROmtglpmqTKN8wMc++l4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}