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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d0568fd8ac07c8abe2907c0a0990c2a78363a499821c367a466a9c4681d804d' 
  AND token = 'Sa6e0GHKpiqZsCl7ZnGNzF7qAf2bIpAjY36SGlSxbYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}