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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0446406240b47ab3ebe3577ebe838a1230470c1006a79a84907e6b47bb3502a7' 
  AND token = 'O1vqS89OvFQsuumxYQVeQ20VL6fQm0X45bXwwKrS7W8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}