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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '217b243032610c08f30bd0aa31d5f7c0bdd30797cbbd721c6c6cbba67cc5e653' 
  AND token = 'Wd8K5Aq/ifhZsYes/+H1zjf9Qc+traPT3o0r7+MdaUo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}