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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '158276d498908f5ff4f7494a079196b4e0e962386543faebc66fbeb26785278b' 
  AND token = 'sQAz1UQvw19G7PgxMd0U3zGpTbwucHt5cdEJQ1aRQbk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}