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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '228b6c71a9fca64a6d4b221a732742457f88641d4b31a620c7d0c2b8bbcb42b2' 
  AND token = 'JMbWm64S85HkbshnCFi7gxjniH8xuRgDpMI/TbxpbiQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}