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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '743167a8b3ea8b267e6a3358616fc19f8a62a3e8ae986b75d815aead1e7bf751' 
  AND token = 'yxyDk7GbHjwPl23ZCaXlaXxeQLEibBu6RqUMLs+Ng40=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}