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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '095e29fac686d1351196d882a9c4da0b5c2b077a140c7f13f7d4d6761c127227' 
  AND token = 'fqXbhg2ooSFDqaownJGFCz5WKyxT25dXiIqJaZ0lBIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}