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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5f07c42d9da4dc2265c95a299623651b5124b286f4fc3792a5a1d1ad22b7c625' 
  AND token = 'JEwnt2AFj3o4VvYl50noiPzYpDEEQ3yJbhCFa4oiX/E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}