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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a6a8143a1f2a3123e632e337b4cd380be0ab03624a01a055e8401c19c63b6dc' 
  AND token = 'ACZ4zBShI1QxXC+4cVMPOBfMzQ1rYD4eUVaeGfFgKRA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}