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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '26e48eabc89cbc9310412381e480263debe67c0d57d9ef253242aca0d946e243' 
  AND token = 'mWrRR5bP3S41CIPWbAXFTalLlMvoi0wr4n6BkuXnFaE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}