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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b9df201f6b9c974f826c95daaa5994b54b08f80d61b06f8f0d7128202357c7c' 
  AND token = 'a1ZlVLB/fYrrs4bZf37WAzIuFhRLT9CO2ajoqxrCuZ0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}