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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '845ca60c097a47872fbb1dccd0fd28b7e9f762393fb79e83c7afb8e0411fd326' 
  AND token = '3kweldmmSuSoAIu52PMhdhrTjkRl34pYVQELPkgWTKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}