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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8d5614aa28a4a4a06e72006955818614ef498059ea4ca9d0a0c455307dd990c1' 
  AND token = 'zJ3B2qZNC9Vgf9z8LgNi5FBIJjMeq3nJlElolNh1N3c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}