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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd2345c44a283f2b15a6eeca59915aba164c21c51f0b0ab57d5c13ddac7aa7d55' 
  AND token = 'vpDVCbuKTCVtFJsnfEjitwgfJej3FmtULtbRJfNHhA4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}