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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f315fc1ad27a73a6ef37fe36986e07f03acd84ff4ee36cb9587329e03d4cabf' 
  AND token = 'blOtpC5ANA9CQMay9/JI5EtTBt4AYOsAlxZHHyOTdqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}