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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57509eb184a9cebcc399c7892ac250f5f0003dcabc3d809c2259d4c7223e42b0' 
  AND token = 'OCAGqbDZZenKeFs/AygjMA4e0v+YZGTiSwuk1yCMzlk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}