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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2af602509b8a13a73002f9f582de9e9018edc7700fab1923021f0b6ee335c47e' 
  AND token = 'JN1Fo0+au5X9bMMY/SXHxdbLGZ0aeZbCe+/sIltejj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}