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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd771721853cd4275c39d0c0c2825c1e52793bc7315cfa8bb6966a2ae1dc10b65' 
  AND token = 'CxE34+dKoCLOFLZ08MCsnrDpntSzA3VUUOJUX1YEr4w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}