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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fa540e8a39b3400d2c06f61d3476c0334d09081f699c03be11c8180538d16ad' 
  AND token = 'diBkHJac/dpUYxVEI61qfRDW56pTfbw1xoS9O1VIoLg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}