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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0388b398fd71b87ed4dfda71b07962bd2df0f40fe4279c743eb5b0f3e0a027b1' 
  AND token = 'Wuw2ap5kssRXczY9VoN4cKFqmF4ptdhz85TLq77h8dI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}