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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec46a99f50d86407bee9a2149b8e0d7220d92ad75e83343013b9896be2d901af' 
  AND token = 'DlMdzKIeEtanjZ7OJLdk01u89Mjny5OGhPY3Tykgibk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}