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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '652b7329b8321ca4828555182afbf12f2e7df2e3678f23c5a3426b792cb3f3a1' 
  AND token = 'lN40+K5CGg7jTZxRhOOfj8WA+otmX1nEBGhPWEQt5Y0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}