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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '885aa7e09093191299eb8c19b3296efd2c8eac9d76f200be65f6cc40369d9b4a' 
  AND token = 'ZSwUmUmjMFbpwaKAGYhdVigvjDRiZe8c0YtNMowXNd4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}