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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e1ffb01b0963f7f08ea07a7f00ccd61c63beb5dd050dad98f684338c57313e0a' 
  AND token = '6+bWyBSRsAm5mabQUIthyMNRBo88XLu+jJCBJukdLIA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}