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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d0f861302d72a5808a9c00e4a35066f3d31e43e2898f0fd4df2245d8944d0a8' 
  AND token = 'rkfVRN0G/0PFsnC179vvqDn5xy7l26nOy3b8iZU6ARM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}