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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '859c41c6bb26bc9dd3fe3b801b801539900e62945335bbbb67300071b5511fd2' 
  AND token = 'KSb2Of3GpVKAMute1OUrcLhJyLyBEVEJLPLRd7KwU8A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}