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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9a2905cdae01c3e5cc470a11c49ee0670f62134957a939be6799b6015cdce535' 
  AND token = 'cenQO0Mkt9ETFm6sSuYz1Z01yfHgaiTMC0TV7jokFA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}