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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70eaed29908dab5e7c77bdb3ffbdb97093f018e494163b5c6fd07ff216d77d1f' 
  AND token = 'k51G3WDp3xgFEl1x5TZJFUwOTrFNHdlCJyREh0LXyAY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}