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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a88191d2282eb5cc917f2e5e2a2dce9b9a6ba1c71b1ff6943187be49afc20950' 
  AND token = 'WDtg2n2oG84cHeJShzrjCpsxDgXUFT5m7Ixe7Uit5Z4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}