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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f161cc48982edbf5f44e6fb82051cae54e3994fd0e70a298c601e6288dcc69c6' 
  AND token = 'yk4FwUPpwfBwRNnnnneuJAGb/pR7FG3L5ZbL2ni8uvA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}