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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3cea2ab5c3023fbb574ba0db5c7e4e004121692628f7f3dbd8cda97097aa8456' 
  AND token = '4H4ej1tKKpshFyrRHYZiRXk+DnAvdFeCPiofU5ITOuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}