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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '40995cba8463a2be49498d7321dd9e845dbeee7b28a09f5f675a5832ae5b5792' 
  AND token = '0/VkCM6OnTG0spJwFqOLDrmzu9bCbDcuaTcK9LdzlM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}