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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46081feab04e2d813e7429f06b71465fc3b35e2f2f46098604bc2749707d5200' 
  AND token = 'M5DPXUU2ECnKBbd735dsgADJZVtIy0tX+vMuJQ1r+oI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}