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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '963f99b9a5ece1c45d2e4238a19b97e3e36fa8e9c192ef92c302d018e068e862' 
  AND token = 'GW1fuHFDz9b9wQw5eVa4dY1nXzgxITu+9a/feMT7LAo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}