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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7489109365313a55c8a0d8d7593f69b8e0846f44a7c936239c9476746651025' 
  AND token = '9EPYeMJXZtHtR+cN0foh+m12oI2oeyEmhUzhb+8LYXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}