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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e47320c9a79a15cb167fe75e33a169dad0ba46d2b78e199d5afcd27a31484094' 
  AND token = 'S9cNe0dtU2juyb9P1RevfRhBJoihBu5/FaTatVImAlY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}