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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa05f26de21e6557219de1643e02c9ad99371eccbfe902abfe0013d6f006a067' 
  AND token = 'vU8C78xb08AgbBEfdtiJcnC7v/jrz+my2KxlvAm61I8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}