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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ea79c4aad633e9c5f1f0d594fa23e16a73244a9224077b23139aa09f37e9eb1' 
  AND token = 'CI+8VS6JS9tAO4lHeHWYG8RKo+RcTA/LakHZaGZxld8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}