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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c4373d33275af5cc2e03a9d9a4f318cc2d7aadd149bcf2087cea865c85a45619' 
  AND token = 'w2Bmqyb91aIEIDbUZrKgU+nru+40QubNCTXYtVrhSUg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}