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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f227099713977c473d8cf2c01f95e239d0edadc76c11a2a0035853123d9a449' 
  AND token = 'Tj7TaNvJxr4fNPfcLFekJLPiLT/THEfizxv7uvJvubE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}