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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '944f9b406d06c134eda55e870011b87bd4ba1e4e51a43ab590cdaf9016fb06a7' 
  AND token = 'yREc1P0FeoQp0wVyh1lduU1wJcE77385F+5Rr29xRVE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}