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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78cc8c11fa4ceaee5c463418afdcb3eb86646c3f8c68a837368c968dc6656011' 
  AND token = '3acL+rEosAgfi1aXNH5pCNASv63e4Dgfcm0sNdMmwvU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}