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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00cb9110bb993dd53be2716a6146a877c1afd099790bf87efdce89db338ac277' 
  AND token = '48ztUXbEfXcS1kxVOSAYARlds71AmIrDrp3qXpjoDXI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}