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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c1f5d295d2f4053be122cb5bc1ce43c18bc377dcff1bfa74dc33723868d5471' 
  AND token = 'JrPgQxkSlaH3FX4+AnVhmYFp0yxhps44wYjWCOMOSRU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}